ISSN 1662-4009 (online)

ey0018.1-16 | Pituitary Function and Viral Diseases | ESPEYB18

1.16 COVID-19 and the pituitary

S Frara , A Allora , L Castellino , L di Filippo , P Loli , A Giustina

Pituitary. 2021 Jun;24(3):465–481. doi: 10.1007/s11102-021-01148-1. PMID: 33939057.Frara et al. review the main endocrine manifestations of COVID-19 with its implications for pituitary diseases. The authors report on the possible direct and indirect involvement of the pituitary gland in COVID-19 infection, and also the impact of COVID-19 on the management of pituitary dise...

ey0017.5-7 | Translational Highlights | ESPEYB17

5.7. RANKL Inhibition in fibrous dysplasia of bone: A preclinical study in a mouse model of the human disease

B Palmisano , E Spica , C Remoli , R Labella , A Di Filippo , S Donsante , F Bini , D Raimondo , F Marinozzi , A Boyde , P Robey , A Corsi , M Riminucci

To read the full abstract: J Bone Miner Res. 2019;34(12):2171–2182.In brief: The effect of RANKL inhibition on fibrous dysplasia development is explored here using a mouse model of a fibrous dysplasia-like disorder. Anti-mouse RANKL monoclonal antibody treatment prevented the development and growth of lesions. However, after discontinuation of anti-mouse ...